DEBBIE-AD: Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease

Gain data to find out if the BBB-ASL in its current state produces measurements of reliability and reproducibility in the brains of healthy volunteers and patients with glioma. Compare new technique with established perfusion technique (DCE, dynamic contrastenhanced MRI) in patients spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol