MRI Research Amsterdam UMC

ASAP (MR Elastography)

We are able to characterize tumor microenvironment, including perfusion, diffusion and hypoxia, using various Magnetic Resonance Imaging (MRI), including 7T 31P MRS. Ultimately, we would like to use these biomarkers to predict which treatments will be most effective for individual cancer patients. Our MRI methods consist of dynamic contrast‐enhanced (DCE), intravoxel incoherent motion (IVIM), MR elastography (ASAP project) and relaxometry derived MRI parameters. At the Spinoza Centre (AMC campus) a 7T MRI is installed and is currently being upgraded with a borecoil for 31P MR spectroscopy. Phosphorus spectroscopy provides a multitude of information on cancer metabolism. We will investigate its added value in treatment prediction and the unravelling of tumor pathophysiology.